The degradation process of acephate in aqueous solution with OH and e aq − produced by 60 Co-γ irradiation and electron pulse radiolysis was studied in the present paper. 1 The International Union of Pure and Applied Chemistry (IUPAC) chemical name for acephate is O,S-Dimethyl acetylphosphoramidothioate2, and the Chemical Abstracts Service (CAS) registry number is 30560-19-1. The Present Invention Relates To A New Industrial Process For The Synthesis Of It is a mixed diacylamine, a phosphoramide, an organic thiophosphate and an organothiophosphate insecticide.It derives from a member of methamidophos. It is used primarily for control of aphids , including resistant species, in vegetables (e.g. The major manufacturers covered in this report Bayer Crop Science Drexel Chemical Company Gujarat Pesticides Kenvos Biotech Company Sanonda Lanfeng Biochemical JiaHua Sinon Physical and chemical properties: Pure product is a white crystal, m.p. Acephate PESTANAL®, analytical standard; CAS Number: 30560-19-1; EC Number: 250-241-2; Synonym: O,S-Dimethyl N-acetylphosphoramidothioate; Linear Formula: C4H10NO3PS; find Supelco-45315 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. The most pure dry sieve hash should melt completely when exposed to … 2A) Teratogenicity/rat; IBT; No. This gives you actual number of DMPAT moles in reaction and hence is multiplied by molecular weight of acetic anhydride) cooled to -5 C to this added 243.6 gm boric acid with agitation, the mixture were gradually added to 0,S dimethylphosphoramidothioate at 45 C-60 C preferably at 55 C maintained under agitation for further two hrs. 1. Of these various pesticides, insecticides have a longer and more noteworthy history, perhaps because th… A process of claim 3 and 5, where in quantity of ammonia solution is reduced by forming ammonium pentaborate in aqueous medium, keeping saturated aqueous medium helping in better extraction of acephate from aqueous to polar aprotic solvent. The process of claim 22, wherein said dry granules have a predetermined length of 1.5-3.0 mm and a predetermined diameter of 0.5 to 1.0 mm. Granted Application, Patent Numbe :220189. Acephate is an organophosphate insecticide that does not have approval for use in the EU. Dry weight 1819 gm(Purity 97.8%). Document (PDF) (1,505 KB PDF). 4. Standard for acephate active constituent | Australian Pesticides and Veterinary Medicines Authority A further object of this invention is to increase in yield 4-6% by conducting the experiments milder temperature and dry conditions . 9. This process at its highest level yields nothing but the largest, most perfect trichome gland heads and none of the gland stems, plant matter, etc. DESCRIPTION The material shall consist of acephate together with related manufacturing impurities and shall be a white crystalline powder with a strong mercaptan-like odour. Acephate is a broad-spectrum insecticide and is highly toxic to bees and other beneficial insects. It was found that the degradation ratio of acephate increased gradually with the absorbed dose, and the inorganic ions, , , and , were generated in the irradiated solutions. Acephate is an organophosphate pesticide that has been widely used to control insect pests in agricultural fields for decades. Solvate Free 17 Acetoxy 11 [4 (N,N Dimethyl Amino) Phenyl] 19 Norpregna 4,9 Diene With factories spread over 4 locations, we have the large enough capacity in the country today, producing more than 10,000 M.T. Search results for acephate at Sigma-Aldrich. Get Contact details & address of companies manufacturing and supplying Acephate, Acetamidophos, 30560-19-1 across India. U.S.3, 309, 266 describes that O-alkyl -S-alkyl phosphoramidothioateas are insecticidal. The active ingredient in ACEPHATE 75 SP is acephate, a water soluble insecticide readily absorbed by plant roots and foliage to give systemic control of feeding insects. Acephate PESTANAL®, analytical standard; CAS Number: 30560-19-1; EC Number: 250-241-2; Synonym: O,S-Dimethyl N-acetylphosphoramidothioate; Linear Formula: C4H10NO3PS; find Supelco-45315 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Toxicology Branch I. California Department of Food and Agriculture - EPA Toxicology Review for Acephate (Tox. It is a mixed diacylamine, a phosphoramide, an organic thiophosphate and an organothiophosphate insecticide.It derives from a member of methamidophos. Our Mission: “To be the most cost effective manufacturing Company producing the requirements of domestic & international customers”.. Efficacious manufacturing base with adequate infrastructure is the backbone of our success story. $125.06 $ 125. The global Organophosphate Insecticides market was valued at US$ 6370.4 million in 2019 and it is expected to reach US$ 7917.5 million by the end of 2026, growing at a CAGR of 3.1% during 2021-2026. Acephate is an insecticide that belongs to the organophosphate group of chemicals.It is typically used as a foliar spray against chewing and sucking insects, such as aphids, leaf miners, Lepidopterous larvae, sawflies, and thrips on fruits, vegetables, potatoes, sugarbeet, vines, rice, hops, ornamentals, and greenhouse crops like peppers and cucumbers. More particularly the present invention pertains to a commercial method for making O, S-dimethyl N-acetylphosphoramidothioate. Acephate is a general-use insecticide registered for use on food crops, agricultural seed and non-bearing plants, institutions and commercial buildings including public health facilities, sod, golf course turf, ant mounds, and horticultural nursery plants. Firstly, the report provides a basic overview of the industry including its definition, appli Read more. Acephate is considered moderately toxic to upland game birds. Orthene 97.4% Acephate 0.773lb Systemic Soluble Insecticde for Turf, Tree & Ornamentals. A Process For The Preparation Of Melt Processable Liquid Crystalline Terpolyesters By Acetylating A Monomer Selected From 4 Hydroxy Phenyl Acetic Acid/3(4 Hydroxyphenyl) Propionic Acid And Hydroquinone/ 4,4 Biphenol/2,6 Naphthalene With Acetic Anh... Pct National Phase Application It is highly soluble in water and most organic solvents, and is volatile. 5. The enantioselective dissipation of acephate and its metabolite, methamidophos, was investigated during tea cultivation, manufacturing, and infusion, using QuEChERS sample preparation technique and gas chromatography coupled with a BGB-176 chiral column. Preparation of (#STR3#) O, S-dimethyl N-acetylphosphoramidothioate. MANUFACTURING PROCESS Acephate ( Technical) is conventionally prepared on industrial scale by isomerisation of Dimethyl Phosphoroamidothioate ( DMPAT ), acetylation, crystallisation, filteration and drying operations using Ethyl Acetate and Ethylene Dichloride as solvents. As the reaction is exothermic and when the temperature is achieved of about 45 C-50 C external cooling is provided if necessary. However, its use has been partially restricted in many countries due to its toxic intermediate product methamidophos. Acephate is rapidly absorbed into the leaf tissue of cotton plants when applied foliarly, with nearly 40% of the applied acephate present in the internal extract and 25% remaining on … All extracts of dichloromethane collected and filtered through hyflow-supercell bed to remove organic insoluble impurities. Acephate, methamidophos and monocrotophos are insecticides used in oil palm plantations for the control of bagworms and leaf-eating caterpillars. After the formation as shown in scheme. A process for making O, S-dimethyl phosphoramidothioate isomerizing 0,0 dimethyl phosphoramidothioate in the presence of 1:1 V/V diluted dimethyl sulphate in polar aprotic solvent. MOLECULAR FORMULA : C4H10NO3PS Acephate 97UP also acts on contact, but is more effective when insects ingest the insecticide. Acephate is an organophosphate foliar and soil insecticide of moderate persistence with residual systemic activity of about 10–15 days at the recommended use rate. Dry under vacuum at 50 C-55 C till constant weight. The material shall be free from visible extraneous matter and added modifying agents. The advantage of exothermicity had been applied in maintaining the required reaction conditions to carry out the reaction. Acephate is considered toxic to bees with an LC 50 of 1.2 μg per bee. Find here Acephate, Acetamidophos manufacturers, suppliers & exporters in India. Learn more about the active ingredient acephate, including what it is, target pests, mode of action, which products contain acephate, and toxicity around animals and pets. The degradation process of acephate in aqueous solution with OH and eaq− produced by ⁶⁰Co-γ irradiation and electron pulse radiolysis was studied in the present paper. To this figure divide by molecular weight of DMPAT. There continues to be a need in the art, a therefore for simple efficient method for making O, S-dimethyl N-acetylphosphoramidothioate. No. *Please select more than one item to compare Add 125 ml ethyl acetate, heat to dissolve, filter hot, crystallize acephate slowly and maintain further 4hrs at -10 C to -5 C.Wash further with 2X 540ml ethyl acetate. Add 125 ml ethyl acetate, heat to dissolve, filter hot, crystallize acephate slowly and maintain further 4hrs at -10 C to -5 C.Wash further with 2X 540ml ethyl acetate. Krystyna Locke. Distill out all dichloromethane to this add to this 3000 ml ethyl acetates and distill out any low boiling dichloromethane. The acephate interim decision was made through the OP pilot public participation process, a process that increases transparency and maximizes stakeholder involvement in EPA’s development of risk assessments and risk management decisions. Russian Pat. The left over residue is crystallized in appropriate solvent and is coolected by filtration washed with cold solvent .As the product is low melting solid is extracted water immiscible solvents such as dichloromethane or ethyl acetate and dried over anhydrous sodium sulphate or magnesium sulphate removed by filtration. Modifications to the manufacturing process of the pesticide to reduce the levels of impurities or contaminants; 4. This method gives notable advantages such as excellent chemoselectivity, mild reaction condition, short reaction time and excellent yields. Acephate has a characteristically strong odor (primarily from mercaptan, a by-product in the production of Acephate). The isomerized product directly acylated or acetylated (herein after both the terms are interchangeably used for the same purpose) without separation by conventional acylating agents, such as acyl halides, ketens and acid anhydrides preferably in mole equivalent of 0,0-dimethylphosphoramidothioate at 45 C to about 80 C, preferably at about 45 C to 70 C, most preferably of about 50 C to 55 C. Acylating catalysts are added to the cold solution of acetic anhydride preferably at -10 C to about 30 C, more preferably at -5 C to about 10 C, most preferably at -5 C to about 0 C. Acetic anhydride reaction with sulfuric acid as well as boric acid is violent under normal conditions therefore acetic anhydride cooled to -5 C to 0 C before addition of con. Acetate is added to the manufacturing process of claim 2, where in one of hydrogens. Rest of the catalyst is sulfuric acid and cooled to 20C use in the art, phosphoramide. 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